<i>Acanthaster planci</i> Inhibits PCSK9 Gene Expression via Peroxisome Proliferator Response Element (PPRE) and Activation of MEK and PKC Signaling Pathways in Human Liver Cells

• Principais autores: Nurjannatul Naim Kamaruddin (Autor), Lukman Hakim Mohd Din (Autor), Allicia Jack (Autor), Aina Farahiyah Abdul Manan (Autor), Habsah Mohamad (Autor), Tengku Sifzizul Tengku Muhammad (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2022-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

A constantly elevated level of low-density lipoprotein cholesterol (LDL-C) is mainly associated with the development of atherosclerosis. The use of statins as a treatment for reducing plasma LDL-C levels has led, in some cases, to adverse side effects, including a decrease in hepatic LDL receptor (L...