Identification of a Novel Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase: In Vitro and In Silico Studies
The enhancement of cholinergic functions via acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition is considered a valuable therapeutic strategy for the treatment of Alzheimer's disease. This study aimed to evaluate the in vitro effect of ZINC390718, previously filtered using...
Saved in:
Main Authors: | Raquel B. M. de Almeida (Author), Deyse B. Barbosa (Author), Mayra R. do Bomfim (Author), Jéssika A. O. Amparo (Author), Bruno S. Andrade (Author), Silvia L. Costa (Author), Joaquín M. Campos (Author), Jorddy N. Cruz (Author), Cleydson B. R. Santos (Author), Franco H. A. Leite (Author), Mariana B. Botura (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2023-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
α-Glucosidase, butyrylcholinesterase and acetylcholinesterase inhibitory activities of phenolic compounds from Carthamus tinctorius L. flowers: In silico and in vitro studies
by: Jawaher A.M. Alotaibi, et al.
Published: (2024) -
Discovery of pyrrole derivatives as acetylcholinesterase-sparing butyrylcholinesterase inhibitor
by: Shouyuan Sun, et al.
Published: (2022) -
Evaluation of N-alkyl isatins and indoles as acetylcholinesterase and butyrylcholinesterase inhibitors
by: Kaitlyn N. Alcorn, et al.
Published: (2024) -
Inhibition of acetylcholinesterase and butyrylcholinesterase with uracil derivatives: kinetic and computational studies
by: Huseyin Cavdar, et al.
Published: (2019) -
Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers
by: I. Caroline Vaaland, et al.
Published: (2023)