Effects of Enzyme Induction and/or Glutathione Depletion on Methimazole Induced Hepatotoxicity in Mice and the Protective Role of N-Acetylcysteine

Purpose: Methimazole is the most convenient drug used in the management of hyperthyroid patients. However, associated with its clinical use is hepatotoxicity as a life threatening adverse effect. The exact mechanism of methimazole-induced hepatotoxicity is still far from clear and no protective agen...

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Main Authors: Reza Heidari (Author), Hossein Babaei (Author), Leila Roshangar (Author), Mohammad Ali Eghbal (Author)
Format: Book
Published: Tabriz University of Medical Sciences, 2014-03-01T00:00:00Z.
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3rd Floor Main Library

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