Effects of Enzyme Induction and/or Glutathione Depletion on Methimazole Induced Hepatotoxicity in Mice and the Protective Role of N-Acetylcysteine

Purpose: Methimazole is the most convenient drug used in the management of hyperthyroid patients. However, associated with its clinical use is hepatotoxicity as a life threatening adverse effect. The exact mechanism of methimazole-induced hepatotoxicity is still far from clear and no protective agen...

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Autores principales: Reza Heidari (Autor), Hossein Babaei (Autor), Leila Roshangar (Autor), Mohammad Ali Eghbal (Autor)
Formato: Libro
Publicado: Tabriz University of Medical Sciences, 2014-03-01T00:00:00Z.
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