Development and Characterization of a Novel Spray-Dried Powder for Inhalation of Cinacalcet HCl Nanoparticles
Background: Administering Cinacalcet HCl (CINA) can be challenging because of its low oral bioavailability (20 to 25%) due mainly to its high first-pass metabolism and poor aqueous solubility. However, nanosuspensions are an effective way of enhancing solubility by reducing size. Furthermore, pulmon...
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| Main Authors: | , , , , |
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| Format: | Book |
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Tabriz University of Medical Sciences,
2024-04-01T00:00:00Z.
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