Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans.

• Principais autores: Parakkal Jovvian George (Autor), Jessica A Hess (Autor), Sonia Jain (Autor), John B Patton (Autor), Tingting Zhan (Autor), Nancy Tricoche (Autor), Bin Zhan (Autor), Maria Elena Bottazzi (Autor), Peter J Hotez (Autor), David Abraham (Autor), Sara Lustigman (Autor)
• Formato: Livro
• Publicado em: Public Library of Science (PLoS), 2019-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

BACKGROUND:The current strategy for the elimination of onchocerciasis is based on annual or bi-annual mass drug administration with ivermectin. However, due to several limiting factors there is a growing concern that elimination of onchocerciasis cannot be achieved solely through the current strateg...