Efficacy of Quetiapine Monotherapy and Combination Therapy for Patients with Bipolar Depression with Mixed Features: A Randomized Controlled Pilot Study

• Hauptverfasser: Zheng Wang (Verfasst von), Danhua Zhang (Verfasst von), Yanli Du (Verfasst von), Yin Wang (Verfasst von), Tingting Huang (Verfasst von), Chee H. Ng (Verfasst von), Huimin Huang (Verfasst von), Yanmeng Pan (Verfasst von), Jianbo Lai (Verfasst von), Shaohua Hu (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2023-02-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Effective pharmacotherapy of bipolar depression with mixed features defined by DSM-5 remains unclear in clinical treatment guidelines. Quetiapine (QTP) and valproate have potential treatment utility but are often inadequate as monotherapy. Meanwhile, the efficacy of combination therapies of QTP plus...