Efficacy of Quetiapine Monotherapy and Combination Therapy for Patients with Bipolar Depression with Mixed Features: A Randomized Controlled Pilot Study

• Main Authors: Zheng Wang (Author), Danhua Zhang (Author), Yanli Du (Author), Yin Wang (Author), Tingting Huang (Author), Chee H. Ng (Author), Huimin Huang (Author), Yanmeng Pan (Author), Jianbo Lai (Author), Shaohua Hu (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Effective pharmacotherapy of bipolar depression with mixed features defined by DSM-5 remains unclear in clinical treatment guidelines. Quetiapine (QTP) and valproate have potential treatment utility but are often inadequate as monotherapy. Meanwhile, the efficacy of combination therapies of QTP plus...