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Conjugation of Amisulpride, an Anti-Psychotic Agent, with 5-Aminosalicylic Acid via an Azo Bond Yields an Orally Active Mutual Prodrug against Rat Colitis

Amisulpride (ASP), an anti-psychotic agent, is a pharmacologically equivalent to sulpiride (SP). Because SP demonstrates anti-ulcer and anti-colitic activities, ASP with an aniline moiety was azo-coupled to salicylic acid to generate 5-(aminoethanoylsulfamoyl)-<i>N</i>-[(1-ethylpyrrolidi...

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Autors principals:	Wooseong Kim (Autor), Dayoon Kim (Autor), Seongkeun Jeong (Autor), Sanghyun Ju (Autor), Hanju Lee (Autor), Soojin Kim (Autor), Jin-Wook Yoo (Autor), In-Soo Yoon (Autor), Yunjin Jung (Autor)
Format:	Llibre
Publicat:	MDPI AG, 2019-11-01T00:00:00Z.
Matèries:	article
Accés en línia:	Connect to this object online.
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