Two novel missense mutations in the myostatin gene identified in Japanese patients with Duchenne muscular dystrophy

• मुख्य लेखकों: Oyazato Yoshinobu (लेखक), Narukage Akiko (लेखक), Saiki Kayoko (लेखक), Takeshima Yasuhiro (लेखक), Nishiyama Atsushi (लेखक), Yagi Mariko (लेखक), Matsuo Masafumi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2007-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Myostatin is a negative regulator of skeletal muscle growth. Truncating mutations in the myostatin gene have been reported to result in gross muscle hypertrophy. Duchenne muscular dystrophy (DMD), the most common lethal muscle wastin...