Two novel missense mutations in the myostatin gene identified in Japanese patients with Duchenne muscular dystrophy

• Автори: Oyazato Yoshinobu (Автор), Narukage Akiko (Автор), Saiki Kayoko (Автор), Takeshima Yasuhiro (Автор), Nishiyama Atsushi (Автор), Yagi Mariko (Автор), Matsuo Masafumi (Автор)
• Формат: Книга
• Опубліковано: BMC, 2007-04-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Myostatin is a negative regulator of skeletal muscle growth. Truncating mutations in the myostatin gene have been reported to result in gross muscle hypertrophy. Duchenne muscular dystrophy (DMD), the most common lethal muscle wastin...