Genetically altered animal models for ATP1A3-related disorders

• Главные авторы: Hannah W. Y. Ng (Автор), Jennifer A. Ogbeta (Автор), Steven J. Clapcote (Автор)
• Формат: ‌
• Опубликовано: The Company of Biologists, 2021-10-01T00:00:00Z.
• Предметы: article
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Within the past 20 years, particularly with the advent of exome sequencing technologies, autosomal dominant and de novo mutations in the gene encoding the neurone-specific α3 subunit of the Na+,K+-ATPase (NKA α3) pump, ATP1A3, have been identified as the cause of a phenotypic continuum of rare neuro...