Optimization and Development of Selective Histone Deacetylase Inhibitor (MPT0B291)-Loaded Albumin Nanoparticles for Anticancer Therapy

• मुख्य लेखकों: Athika Darumas Putri (लेखक), Pai-Shan Chen (लेखक), Yu-Lin Su (लेखक), Jia-Pei Lin (लेखक), Jing-Ping Liou (लेखक), Chien-Ming Hsieh (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Histone deacetylase (HDAC) inhibitors have emerged as a new class of antitumor agent for various types of tumors. MPT0B291, a novel selective inhibitor of HDAC6, demonstrated significant antiproliferative activity in various human cancer cell types. However, MPT0B291 has very low water solubility, w...