Optimization and Development of Selective Histone Deacetylase Inhibitor (MPT0B291)-Loaded Albumin Nanoparticles for Anticancer Therapy

• Asıl Yazarlar: Athika Darumas Putri (Yazar), Pai-Shan Chen (Yazar), Yu-Lin Su (Yazar), Jia-Pei Lin (Yazar), Jing-Ping Liou (Yazar), Chien-Ming Hsieh (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Histone deacetylase (HDAC) inhibitors have emerged as a new class of antitumor agent for various types of tumors. MPT0B291, a novel selective inhibitor of HDAC6, demonstrated significant antiproliferative activity in various human cancer cell types. However, MPT0B291 has very low water solubility, w...