Rapamycin improves the quality and developmental competence of mice oocytes by promoting DNA damage repair during in vitro maturation

• Главные авторы: Qiyu Yang (Автор), Qingsong Xi (Автор), Meng Wang (Автор), Rui Long (Автор), Juan Hu (Автор), Zhou Li (Автор), Xinling Ren (Автор), Lixia Zhu (Автор), Lei Jin (Автор)
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• Опубликовано: BMC, 2022-04-01T00:00:00Z.
• Предметы: article
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Abstract Background Increasing evidence has shown that the mammalian target of rapamycin (mTOR) pathway plays a critical role in oocyte meiosis and embryonic development, however, previous studies reporting the effects of rapamycin on oocyte IVM showed different or even opposite results, and the spe...