Rapamycin improves the quality and developmental competence of mice oocytes by promoting DNA damage repair during in vitro maturation

• Hauptverfasser: Qiyu Yang (Verfasst von), Qingsong Xi (Verfasst von), Meng Wang (Verfasst von), Rui Long (Verfasst von), Juan Hu (Verfasst von), Zhou Li (Verfasst von), Xinling Ren (Verfasst von), Lixia Zhu (Verfasst von), Lei Jin (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2022-04-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background Increasing evidence has shown that the mammalian target of rapamycin (mTOR) pathway plays a critical role in oocyte meiosis and embryonic development, however, previous studies reporting the effects of rapamycin on oocyte IVM showed different or even opposite results, and the spe...