Rapamycin improves the quality and developmental competence of mice oocytes by promoting DNA damage repair during in vitro maturation

• Main Authors: Qiyu Yang (Author), Qingsong Xi (Author), Meng Wang (Author), Rui Long (Author), Juan Hu (Author), Zhou Li (Author), Xinling Ren (Author), Lixia Zhu (Author), Lei Jin (Author)
• Format: Book
• Published: BMC, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Increasing evidence has shown that the mammalian target of rapamycin (mTOR) pathway plays a critical role in oocyte meiosis and embryonic development, however, previous studies reporting the effects of rapamycin on oocyte IVM showed different or even opposite results, and the spe...