The Multifaceted Profile of Thyroid Disease in the Background of <i>DICER1</i> Germline and Somatic Mutations: Then, Now and Future Perspectives

• Main Authors: Sule Canberk (Author), Marcelo Correia (Author), Ana Rita Lima (Author), Massimo Bongiovanni (Author), Manuel Sobrinho-Simões (Author), Paula Soares (Author), Valdemar Máximo (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

DICER1 protein is a member of the ribonuclease (RNAse) III family with a key role in the biogenesis of microRNAs (miRNA) and in microRNA processing, potentially affecting gene regulation at the post-transcriptional level. The role of DICER1 and its relevance to thyroid cellular processes and tumorig...