The Multifaceted Profile of Thyroid Disease in the Background of <i>DICER1</i> Germline and Somatic Mutations: Then, Now and Future Perspectives

• Auteurs principaux: Sule Canberk (Auteur), Marcelo Correia (Auteur), Ana Rita Lima (Auteur), Massimo Bongiovanni (Auteur), Manuel Sobrinho-Simões (Auteur), Paula Soares (Auteur), Valdemar Máximo (Auteur)
• Format: Livre
• Publié: MDPI AG, 2022-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

DICER1 protein is a member of the ribonuclease (RNAse) III family with a key role in the biogenesis of microRNAs (miRNA) and in microRNA processing, potentially affecting gene regulation at the post-transcriptional level. The role of DICER1 and its relevance to thyroid cellular processes and tumorig...