Convergent synthesis of new N -substituted 2-{[5-(1H -indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamides as suitable therapeutic agents

• Príomhchruthaitheoirí: Kaniz Rubab (Údar), Muhammad Athar Abbasi (Údar), Aziz- (Údar), Sabahat Zahra Siddiqui (Údar), Muhammad Ashraf (Údar), Ayesha Shaukat (Údar), Irshad Ahmad (Údar), Muhammad Arif Lodhi (Údar), Farman Ali Khan (Údar), Muhammad Shahid (Údar), Muhammad Nadeem Akhtar (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Universidade de São Paulo, 2015-12-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

abstract A series of N-substituted 2-{[5-(1H-indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamides (8a-w) was synthesized in three steps. The first step involved the sequential conversion of 2-(1H-indol-3-yl)acetic acid (1) to ester (2) followed by hydrazide (3) formation and finally cyclizatio...