Convergent synthesis of new N -substituted 2-{[5-(1H -indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamides as suitable therapeutic agents

• Päätekijät: Kaniz Rubab (Tekijä), Muhammad Athar Abbasi (Tekijä), Aziz- (Tekijä), Sabahat Zahra Siddiqui (Tekijä), Muhammad Ashraf (Tekijä), Ayesha Shaukat (Tekijä), Irshad Ahmad (Tekijä), Muhammad Arif Lodhi (Tekijä), Farman Ali Khan (Tekijä), Muhammad Shahid (Tekijä), Muhammad Nadeem Akhtar (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Universidade de São Paulo, 2015-12-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

abstract A series of N-substituted 2-{[5-(1H-indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamides (8a-w) was synthesized in three steps. The first step involved the sequential conversion of 2-(1H-indol-3-yl)acetic acid (1) to ester (2) followed by hydrazide (3) formation and finally cyclizatio...