Based on whole-exome sequencing to explore the rule of Herceptin and TKI resistance in breast cancer patients

• Main Authors: Liantao Guo (Author), Hong Cheng (Author), Jianhua Liu (Author), Weikang Shao (Author), Lan Luo (Author), Weijie Zheng (Author), Shengrong Sun (Author), Deguang Kong (Author), Chuang Chen (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Breast cancer is the second leading cause of cancer-related death in women, and drug resistance during treatment is a major challenge. However, the mechanisms underlying drug resistance are not fully understood. Here we applied whole-exome sequencing (WES) to clarify resistant ru...