Based on whole-exome sequencing to explore the rule of Herceptin and TKI resistance in breast cancer patients

• Egile Nagusiak: Liantao Guo (Egilea), Hong Cheng (Egilea), Jianhua Liu (Egilea), Weikang Shao (Egilea), Lan Luo (Egilea), Weijie Zheng (Egilea), Shengrong Sun (Egilea), Deguang Kong (Egilea), Chuang Chen (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2024-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Breast cancer is the second leading cause of cancer-related death in women, and drug resistance during treatment is a major challenge. However, the mechanisms underlying drug resistance are not fully understood. Here we applied whole-exome sequencing (WES) to clarify resistant ru...