Investigation of a fully mechanistic physiologically based pharmacokinetics model of absorption to support predictions of milk concentrations in breastfeeding women and the exposure of infants: A case study for albendazole

Abstract Due to limited non‐clinical and clinical data, European guidance recommends to discontinue breastfeeding when taking albendazole. The aim of this study was to consider the use of PBPK modeling to support the expected exposure in breastfed infants. A fully mechanistic PBPK approach was used...

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Bibliographic Details
Main Authors: Susan Cole (Author), Maria Malamatari (Author), Andrew Butler (Author), Mahnoor Arshad (Author), Essam Kerwash (Author)
Format: Book
Published: Wiley, 2024-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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