Combined targeting of pathways regulating synaptic formation and autophagy attenuates Alzheimer's disease pathology in mice
All drug trials completed to date have fallen short of meeting the clinical endpoint of significantly slowing cognitive decline in Alzheimer's disease (AD) patients. In this study, we repurposed two FDA-approved drugs, Fasudil and Lonafarnib, targeting synaptic formation (i.e., Wnt signaling) a...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Frontiers Media S.A.,
2022-08-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |