Immunogenicity and efficacy following sequential parenterally-administered doses of Salmonella Enteritidis COPS:FliC glycoconjugates in infant and adult mice.

• Main Authors: Scott M Baliban (Author), Brittany Curtis (Author), Deanna Toema (Author), Sharon M Tennant (Author), Myron M Levine (Author), Marcela F Pasetti (Author), Raphael Simon (Author)
• Format: Knjiga
• Izdano: Public Library of Science (PLoS), 2018-05-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

In sub-Saharan Africa, invasive nontyphoidal Salmonella (iNTS) infections with serovars S. Enteritidis, S. Typhimurium and I 4,[5],12:i:- are widespread in children < 5 years old. Development of an efficacious vaccine would provide an important public health tool to prevent iNTS disease in this p...