Immunogenicity and efficacy following sequential parenterally-administered doses of Salmonella Enteritidis COPS:FliC glycoconjugates in infant and adult mice.

• Autores principales: Scott M Baliban (Autor), Brittany Curtis (Autor), Deanna Toema (Autor), Sharon M Tennant (Autor), Myron M Levine (Autor), Marcela F Pasetti (Autor), Raphael Simon (Autor)
• Formato: Libro
• Publicado: Public Library of Science (PLoS), 2018-05-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

In sub-Saharan Africa, invasive nontyphoidal Salmonella (iNTS) infections with serovars S. Enteritidis, S. Typhimurium and I 4,[5],12:i:- are widespread in children < 5 years old. Development of an efficacious vaccine would provide an important public health tool to prevent iNTS disease in this p...