3,4-Methylenedioxy-β-Nitrostyrene Alleviates Dextran Sulfate Sodium-Induced Mouse Colitis by Inhibiting the NLRP3 Inflammasome

• Autores principales: Juanjuan Zheng (Autor), Zhongxin Jiang (Autor), Yue Song (Autor), Shu Huang (Autor), Yuzhang Du (Autor), Xiaobao Yang (Autor), Yan Xiao (Autor), Zhihui Ma (Autor), Dakang Xu (Autor), Jing Li (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Inflammatory bowel disease (IBD) has been reported to be associated with NLRP3 inflammasome activation. Therefore inhibiting inflammasome activation could be a new approach to treat IBD. Inflammasome inhibitors NLRP3-IN-2, JC124, and 3,4-methylenedioxy-β-nitrostyrene (MNS) were previously reported t...