The In Vivo Granulopoietic Response to Dexamethasone Injection Is Abolished in Perforin-Deficient Mutant Mice and Corrected by Lymphocyte Transfer from Nonsensitized Wild-Type Donors

• Hoofdauteurs: Pedro Xavier-Elsas (Auteur), Cássio Luiz Coutinho Almeida da Silva (Auteur), Bruno Marques Vieira (Auteur), Daniela Masid- (Auteur), Túlio Queto (Auteur), Bianca de Luca (Auteur), Thiago Soares de Souza Vieira (Auteur), Maria Ignez C. Gaspar-Elsas (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2015-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Exogenously administered glucocorticoids enhance eosinophil and neutrophil granulocyte production from murine bone-marrow. A hematological response dependent on endogenous glucocorticoids underlies bone-marrow eosinophilia induced by trauma or allergic sensitization/challenge. We detected a defect i...