The In Vivo Granulopoietic Response to Dexamethasone Injection Is Abolished in Perforin-Deficient Mutant Mice and Corrected by Lymphocyte Transfer from Nonsensitized Wild-Type Donors

• Główni autorzy: Pedro Xavier-Elsas (Autor), Cássio Luiz Coutinho Almeida da Silva (Autor), Bruno Marques Vieira (Autor), Daniela Masid- (Autor), Túlio Queto (Autor), Bianca de Luca (Autor), Thiago Soares de Souza Vieira (Autor), Maria Ignez C. Gaspar-Elsas (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2015-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Exogenously administered glucocorticoids enhance eosinophil and neutrophil granulocyte production from murine bone-marrow. A hematological response dependent on endogenous glucocorticoids underlies bone-marrow eosinophilia induced by trauma or allergic sensitization/challenge. We detected a defect i...