Effects of Decomplexation Rates on Ternary Gene Complex Transfection with <i>α</i>-Poly(<span style="font-variant: small-caps">l</span>-Lysine) or <i>ε</i>-Poly(<span style="font-variant: small-caps">l</span>-Lysine) as a Decomplexation Controller in An Easy-To-Transfect Cell or A Hard-To-Transfect Cell

• Asıl Yazarlar: Kyoungnam Kim (Yazar), Kitae Ryu (Yazar), Hana Cho (Yazar), Min Suk Shim (Yazar), Yong-Yeon Cho (Yazar), Joo Young Lee (Yazar), Hye Suk Lee (Yazar), Han Chang Kang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2020-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The tight binding of pDNA with a cationic polymer is the crucial requirement that prevents DNA degradation from undesired DNase attack to safely deliver the pDNA to its target site. However, cationic polymer-mediated strong gene holding limits pDNA dissociation from the gene complex, resulting in a...