Ultrasound Assisted Exosomal Delivery of Tissue Responsive mRNA for Enhanced Efficacy and Minimized Off-Target Effects

Exosome-mediated nucleic acids delivery has been emerging as a promising strategy for gene therapy. However, the intrinsic off-target effects due to non-specific uptake of exosomes by other tissues remain the big hurdle for clinical application. In this study, we aimed to enhance the efficacy and mi...

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Hlavní autoři: Wenqi Sun (Autor), Changyang Xing (Autor), Lianbi Zhao (Autor), Ping Zhao (Autor), Guodong Yang (Autor), Lijun Yuan (Autor)
Médium: Kniha
Vydáno: Elsevier, 2020-06-01T00:00:00Z.
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