Synthesis and biological evaluation of the novel chrysin prodrug for non-alcoholic fatty liver disease treatment

• Asıl Yazarlar: Ruiming Zhang (Yazar), Chuanyue Gao (Yazar), Mingxing Hu (Yazar), Xingxing Wang (Yazar), Shuoyuan Li (Yazar), Zhenmei An (Yazar), Xifei Yang (Yazar), Yongmei Xie (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2024-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background: Chrysin (5,7-dihydroxyflavone) is a natural flavonoid that has been reported as a potential treatment for non-alcoholic fatty liver disease (NAFLD). However, extensive phase II metabolism and poor aqueous solubility led to a decrease in the chrysin concentration in the blood after oral a...