Non-Effective Improvement of Absorption for Some Nanoparticle Formulations Explained by Permeability under Non-Sink Conditions

We evaluated the in vitro permeability of nanoparticle formulations of high and low lipophilic compounds under non-sink conditions, wherein compounds are not completely dissolved. The permeability of the highly lipophilic compound, griseofulvin, was improved by about 30% due to nanonization under no...

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Main Authors: Kazuya Sugita (Author), Noriyuki Takata (Author), Etsuo Yonemochi (Author)
Format: Book
Published: MDPI AG, 2022-04-01T00:00:00Z.
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3rd Floor Main Library

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