Design, synthesis, and biological evaluation of biotinylated colchicine derivatives as potential antitumor agents

• প্রধান লেখক: Chao Wang (লেখক), Yujing Zhang (লেখক), Zeyu Wang (লেখক), Yuelin Li (লেখক), Qi Guan (লেখক), Dongming Xing (লেখক), Weige Zhang (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Chemical drug design based on the biochemical characteristics of cancer cells has become an important strategy for discovering new anti-tumour drugs to improve tumour targeting effects and reduce off-target toxicities. Colchicine is one of the most prominent and historically microtubule-targeting dr...