TRPC1 contributes to endotoxemia-induced myocardial dysfunction via mediating myocardial apoptosis and autophagy

• Main Authors: Wen Tian (Author), Shao-Yuan Liu (Author), Meng Zhang (Author), Jing-Ru Meng (Author), Na Tang (Author), Ying-Da Feng (Author), Yang Sun (Author), Yuan-Yuan Gao (Author), Lei Zhou (Author), Wei Cao (Author), Xiao-Qiang Li (Author)
• Format: Book
• Published: Elsevier, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cardiac dysfunction is a vital complication of endotoxemia (ETM) with limited therapeutic options. Transient receptor potential canonical channel (TRPC)1 was involved in various heart diseases. While, the role of TRPC1 in ETM-induced cardiac dysfunction remains to be defined. In this study, we found...