TRPC1 contributes to endotoxemia-induced myocardial dysfunction via mediating myocardial apoptosis and autophagy

• Principais autores: Wen Tian (Autor), Shao-Yuan Liu (Autor), Meng Zhang (Autor), Jing-Ru Meng (Autor), Na Tang (Autor), Ying-Da Feng (Autor), Yang Sun (Autor), Yuan-Yuan Gao (Autor), Lei Zhou (Autor), Wei Cao (Autor), Xiao-Qiang Li (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2022-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Cardiac dysfunction is a vital complication of endotoxemia (ETM) with limited therapeutic options. Transient receptor potential canonical channel (TRPC)1 was involved in various heart diseases. While, the role of TRPC1 in ETM-induced cardiac dysfunction remains to be defined. In this study, we found...