Novel mesothelin-targeted chimeric antigen receptor-modified UNKT cells are highly effective in inhibiting tumor progression

• Автори: Wei Jiang (Автор), Guosheng Gu (Автор), Yumin Zhang (Автор), Yushuai Song (Автор), Ming Shi (Автор), Gang Wang (Автор), Huizhong Li (Автор), Tingting Tao (Автор), Jianhua Qin (Автор), Xianliang Li (Автор), Hongtao Jia (Автор), Feng Jiao (Автор), Weidong Xu (Автор), Xiaoyi Huang (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2023-11-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

The design of chimeric antigen receptors (CAR) significantly enhances the antitumor efficacy of T cells. Although some CAR-T products have been approved by FDA in treating hematological tumors, adoptive immune therapy still faces many difficulties and challenges in the treatment of solid tumors. In...