Synthesis of 4,4'-(4-Formyl-1<i>H</i>-pyrazole-1,3-diyl)dibenzoic Acid Derivatives as Narrow Spectrum Antibiotics for the Potential Treatment of <i>Acinetobacter Baumannii</i> Infections

• Главные авторы: Evan Delancey (Автор), Devin Allison (Автор), Hansa Raj KC (Автор), David F. Gilmore (Автор), Todd Fite (Автор), Alexei G. Basnakian (Автор), Mohammad A. Alam (Автор)
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• Опубликовано: MDPI AG, 2020-09-01T00:00:00Z.
• Предметы: article
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<i>Acinetobacter baumannii</i> has emerged as one of the most lethal drug-resistant bacteria in recent years. We report the synthesis and antimicrobial studies of 25 new pyrazole-derived hydrazones. Some of these molecules are potent and specific inhibitors of <i>A. baumannii</i...