Synthesis of 4,4'-(4-Formyl-1<i>H</i>-pyrazole-1,3-diyl)dibenzoic Acid Derivatives as Narrow Spectrum Antibiotics for the Potential Treatment of <i>Acinetobacter Baumannii</i> Infections

• Main Authors: Evan Delancey (Author), Devin Allison (Author), Hansa Raj KC (Author), David F. Gilmore (Author), Todd Fite (Author), Alexei G. Basnakian (Author), Mohammad A. Alam (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>Acinetobacter baumannii</i> has emerged as one of the most lethal drug-resistant bacteria in recent years. We report the synthesis and antimicrobial studies of 25 new pyrazole-derived hydrazones. Some of these molecules are potent and specific inhibitors of <i>A. baumannii</i...