A novel Mcl-1 inhibitor synergizes with venetoclax to induce apoptosis in cancer cells
Abstract Background Evading apoptosis by overexpression of anti-apoptotic Bcl-2 family proteins is a hallmark of cancer cells and the Bcl-2 selective inhibitor venetoclax is widely used in the treatment of hematologic malignancies. Mcl-1, another anti-apoptotic Bcl-2 family member, is recognized as...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
BMC,
2023-01-01T00:00:00Z.
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