Mitofusin 2 Promotes Apoptosis of CD4+ T Cells by Inhibiting Autophagy in Sepsis

• Hoofdauteurs: Lan Ying (Auteur), Guang-Ju Zhao (Auteur), You Wu (Auteur), He-Liang Ke (Auteur), Guang-Liang Hong (Auteur), Hui Zhang (Auteur), Ning Dong (Auteur), Yao Wu (Auteur), Yong-Ming Yao (Auteur), Zhong-Qiu Lu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2017-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Apoptosis of CD4+ T cells is a primary pathophysiological mechanism of immune dysfunction in the pathogenesis of sepsis. Mitofusin 2 (Mfn2), an integral mitochondrial outer membrane protein, has been confirmed to be associated with cellular metabolism, proliferation, and apoptosis. The function of M...