Mitofusin 2 Promotes Apoptosis of CD4+ T Cells by Inhibiting Autophagy in Sepsis

• Asıl Yazarlar: Lan Ying (Yazar), Guang-Ju Zhao (Yazar), You Wu (Yazar), He-Liang Ke (Yazar), Guang-Liang Hong (Yazar), Hui Zhang (Yazar), Ning Dong (Yazar), Yao Wu (Yazar), Yong-Ming Yao (Yazar), Zhong-Qiu Lu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2017-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Apoptosis of CD4+ T cells is a primary pathophysiological mechanism of immune dysfunction in the pathogenesis of sepsis. Mitofusin 2 (Mfn2), an integral mitochondrial outer membrane protein, has been confirmed to be associated with cellular metabolism, proliferation, and apoptosis. The function of M...