Connexin 43 plays an important role in the transformation of cholangiocytes with Clonochis sinensis excretory-secretory protein and N-nitrosodimethylamine.
BACKGROUND:Clonorchis sinensis is a group I bio-carcinogen responsible for cholangiocarcinoma (CHCA) in humans. However, the mechanism by which C. sinensis promotes carcinogenesis is unclear. METHODOLOGY:Using the human cholangiocyte line H69, we investigated cell proliferation and gap junction prot...
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Public Library of Science (PLoS),
2019-04-01T00:00:00Z.
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