Connexin 43 plays an important role in the transformation of cholangiocytes with Clonochis sinensis excretory-secretory protein and N-nitrosodimethylamine.

• Autores principales: Eun-Min Kim (Autor), Young Mee Bae (Autor), Min-Ho Choi (Autor), Sung-Tae Hong (Autor)
• Formato: Libro
• Publicado: Public Library of Science (PLoS), 2019-04-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

BACKGROUND:Clonorchis sinensis is a group I bio-carcinogen responsible for cholangiocarcinoma (CHCA) in humans. However, the mechanism by which C. sinensis promotes carcinogenesis is unclear. METHODOLOGY:Using the human cholangiocyte line H69, we investigated cell proliferation and gap junction prot...