Formulation Characterization and Pharmacokinetic Evaluation of Amorphous Solid Dispersions of Dasatinib

• मुख्य लेखकों: Sathish Dharani (लेखक), Eman M. Mohamed (लेखक), Tahir Khuroo (लेखक), Ziyaur Rahman (लेखक), Mansoor A. Khan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The aim of this study was to improve the physicochemical properties and oral bioavailability of dasatinib (DST) by the amorphous solid dispersion (ASD) approach using cellulose acetate butyrate (CAB) as a carrier. Various formulations of ASD (DST:CAB 1:1 to 1:5) were prepared by the solvent evaporat...