Formulation Characterization and Pharmacokinetic Evaluation of Amorphous Solid Dispersions of Dasatinib

• Asıl Yazarlar: Sathish Dharani (Yazar), Eman M. Mohamed (Yazar), Tahir Khuroo (Yazar), Ziyaur Rahman (Yazar), Mansoor A. Khan (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The aim of this study was to improve the physicochemical properties and oral bioavailability of dasatinib (DST) by the amorphous solid dispersion (ASD) approach using cellulose acetate butyrate (CAB) as a carrier. Various formulations of ASD (DST:CAB 1:1 to 1:5) were prepared by the solvent evaporat...