Development of a novel radiofluorinated riboflavin probe for riboflavin receptor-targeting PET imaging

• Main Authors: Jindian Li (Author), Juno Van Valkenburgh (Author), Jianyang Fang (Author), Deliang Zhang (Author), Yingxi Chen (Author), Quan Chen (Author), Guorong Jia (Author), Austin Z. Chen (Author), Xianzhong Zhang (Author), Kai Chen (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Riboflavin receptor 3 (RFVT3) is a key protein in energetic metabolism reprogramming and is overexpressed in multiple cancers involved in malignant proliferation, angiogenesis, chemotherapy resistance, and immunosuppression. To enable non-invasive real-time quantification of RFVT3 in tumors, we soug...