Development of a novel radiofluorinated riboflavin probe for riboflavin receptor-targeting PET imaging

• Автори: Jindian Li (Автор), Juno Van Valkenburgh (Автор), Jianyang Fang (Автор), Deliang Zhang (Автор), Yingxi Chen (Автор), Quan Chen (Автор), Guorong Jia (Автор), Austin Z. Chen (Автор), Xianzhong Zhang (Автор), Kai Chen (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2022-09-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Riboflavin receptor 3 (RFVT3) is a key protein in energetic metabolism reprogramming and is overexpressed in multiple cancers involved in malignant proliferation, angiogenesis, chemotherapy resistance, and immunosuppression. To enable non-invasive real-time quantification of RFVT3 in tumors, we soug...