Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome.

• প্রধান লেখক: Monica Chandra (লেখক), Sara Đaković (লেখক), Konstantina Foti (লেখক), Johan P Zeelen (লেখক), Monique van Straaten (লেখক), Francisco Aresta-Branco (লেখক), Eliane Tihon (লেখক), Nicole Lübbehusen (লেখক), Thomas Ruppert (লেখক), Lucy Glover (লেখক), F Nina Papavasiliou (লেখক), C Erec Stebbins (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Public Library of Science (PLoS), 2023-02-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

During infection of mammalian hosts, African trypanosomes thwart immunity using antigenic variation of the dense Variant Surface Glycoprotein (VSG) coat, accessing a large repertoire of several thousand genes and pseudogenes, and switching to antigenically distinct copies. The parasite is transferre...