Dysregulated phosphatidylinositol signaling promotes endoplasmic-reticulum-stress-mediated intestinal mucosal injury and inflammation in zebrafish

• Главные авторы: Prakash C. Thakur (Автор), Jon M. Davison (Автор), Carsten Stuckenholz (Автор), Lili Lu (Автор), Nathan Bahary (Автор)
• Формат: ‌
• Опубликовано: The Company of Biologists, 2014-01-01T00:00:00Z.
• Предметы: article
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Dysregulated phosphatidylinositol (PI) signaling has been implicated in human gastrointestinal (GI) malignancies and inflammatory states, underlining the need to study pathophysiological roles of PI in an in vivo genetic model. Here, we study the significance of PI in GI pathophysiology using the ze...