MLN4924 Treatment Diminishes Excessive Lipid Storage in High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease (NAFLD) by Stimulating Hepatic Mitochondrial Fatty Acid Oxidation and Lipid Metabolites

• Главные авторы: Mengxiao Ge (Автор), Linlin Huang (Автор), Yinjun Ma (Автор), Shuangyi Sun (Автор), Lijun Wu (Автор), Wei Xu (Автор), Dongqin Yang (Автор)
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• Опубликовано: MDPI AG, 2022-11-01T00:00:00Z.
• Предметы: article
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MLN4924 is a selective neddylation inhibitor that has shown great potential in treating several cancer and metabolic diseases, including obesity. However, it remains largely unknown whether MLN4924 has similar effect on non-alcoholic liver disease (NAFLD), which is closely associated with metabolic...